HRT and the menopause
Menopause is when you stop having periods, which usually happens between the ages of 45 and 55.
During the menopause, there is a sharp decrease in the amount of oestrogen (known as oestrogen depletion) and progesterone produced by the ovaries.
As well as causing irregular periods during the menopausal transition, oestrogen depletion causes the characteristic symptoms of menopause, such as hot flushes and night sweats, which are known as ‘vasomotor symptoms’. It can also cause mood changes.